Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722556 | 0.86 | LOXL2 (0.44) | LOXL2GRM5FFAR1ASIC3 | |
| SCHEMBL4460258 | 0.84 | GRM5 (0.50) | GRM5 | |
| SCHEMBL4457929 | 0.80 | GRM5 (0.56) | GRM5 | |
| SCHEMBL319482 | 0.78 | LOXL2 (0.48) | LOXL2GRM5 | |
| SCHEMBL30335660 | 0.78 | LOXL2 (0.48) | LOXL2GRM5 | |
| SCHEMBL11782098 | 0.78 | LOXL2 (0.73) | LOXL2FFAR1ASIC3PLAU | |
| SCHEMBL4454176 | 0.77 | ALDH1A1 (0.54) | GRM5 | |
| SCHEMBL2758337 | 0.77 | TSHR (0.50) | GRM5 | |
| SCHEMBL4454587 | 0.77 | HAO1 (0.48) | GRM5 | |
| Water SCHEMBL5709165 | 0.75 | LOXL2 (1.00) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163667-A | Phenylacetylene compounds | MERCK & CO INC (US) | 2008-04-16 | — | — | CN | disclosed |