Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | IKBKB | O14920 | 6/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.60 |
| ▸ | CDK8 | P49336 | 12/20 | 0.56 |
| ▸ | CDK19 | Q9BWU1 | 5/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723169 | 0.88 | IKBKB (0.57) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL16071477 | 0.86 | KDM4E (0.65) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL5235050 | 0.82 | IKBKB (0.61) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL5234359 | 0.79 | ALDH1A1 (0.60) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL5236613 | 0.79 | ALDH1A1 (0.60) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL27723170 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL5236334 | 0.79 | ALDH1A1 (0.69) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL16071472 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL427267 | 0.76 | ALDH1A1 (1.00) | KDM4EALDH1A1HTTHPGDALOX15 | |
| SCHEMBL5234057 | 0.76 | ALDH1A1 (0.69) | KDM4EALDH1A1HTTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100386329-C | Substituted 3-amino-thieno(2,3-b)pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMA (US) | 2008-05-07 | — | — | CN | disclosed |