Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506049 | 0.86 | PGR (0.44) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL5502831 | 0.79 | ALDH1A1 (0.38) | PGRNR3C1ARNR3C2KDM4E | |
| SCHEMBL5506748 | 0.75 | PGR (0.39) | PGRNR3C1ARNR3C2 | |
| SCHEMBL27685680 | 0.75 | BRD4 (0.39) | PGRNR3C1 | |
| SCHEMBL5506240 | 0.74 | PGR (0.39) | PGRNR3C1ARNR3C2 | |
| SCHEMBL5502297 | 0.73 | PGR (0.56) | PGRNR3C1ARNR3C2ALDH1A1 | |
| SCHEMBL5500965 | 0.72 | NR3C1 (0.41) | PGRNR3C1NR3C2KDM4EALDH1A1 | |
| SCHEMBL5503508 | 0.72 | PGR (0.59) | PGRNR3C1ESR1KDM4EALDH1A1 | |
| SCHEMBL5498846 | 0.72 | PGR (0.43) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL5501313 | 0.71 | AR (0.37) | PGRNR3C1ARKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018552-A | Intracellular receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2007-08-15 | — | — | CN | claimed |
| CN-101018552-A | Intracellular receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2007-08-15 | — | — | CN | disclosed |