Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.62 |
| ▸ | ACHE | P22303 | 11/20 | 0.62 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704563 | 0.82 | HSD17B3 (0.53) | KDM4EALDH1A1NPC1 | |
| SCHEMBL27704593 | 0.79 | MAOB (0.71) | MAOBACHEMAOAKDM4EMEN1 | |
| SCHEMBL7432074 | 0.78 | ACHE (1.00) | MAOBACHEMAOA | |
| SCHEMBL4209959 | 0.77 | MAOA (0.55) | MAOBACHEMAOANPC1CASP3 | |
| SCHEMBL864308 | 0.73 | HDAC1 (0.61) | MAOBKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2761681 | 0.72 | MAOB (0.62) | MAOBACHEMAOAKDM4EMEN1 | |
| SCHEMBL24470960 | 0.71 | CASP3 (0.59) | MAOBMAOAKDM4EMEN1ALDH1A1 | |
| SCHEMBL29712970 | 0.71 | CASP3 (0.59) | MAOBMAOAKDM4EMEN1ALDH1A1 | |
| SCHEMBL30629178 | 0.70 | MAOB (1.00) | MAOBACHEMAOAKDM4EALDH1A1 | |
| SCHEMBL5618504 | 0.69 | MAOB (0.77) | MAOBACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137638-A | Substituted aminoalkyl-and amidoalkyl-benzopyran derivatives | NEWRON PHARM SPA (IT) | 2008-03-05 | — | — | CN | disclosed |