Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895889 | 0.87 | CA2 (0.52) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL27666733 | 0.85 | CA2 (0.46) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL27666728 | 0.85 | STAT3 (0.42) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL7864030 | 0.80 | BACE1 (0.44) | STAT3CYP2C9CDK2TTR | |
| SCHEMBL27895662 | 0.79 | STAT3 (0.41) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL30626032 | 0.79 | FABP4 (0.44) | CA2CA1CA9CA12CA6 | |
| SCHEMBL27561452 | 0.77 | TTR (0.53) | CA2CA1CA9CA12CA6 | |
| SCHEMBL8976123 | 0.77 | CA2 (0.52) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL4759798 | 0.77 | CASP1 (0.48) | CA2CA1CA9CA12STAT3 | |
| SCHEMBL2964281 | 0.77 | CA2 (0.61) | CA2CA1CA9CA12STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101172958-A | N,N*-2(2substituted phenyl) derivant of - 4-methoxy-1,3-benzol diamide and use of the same | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-07 | — | — | CN | claimed |
| CN-101172958-A | N,N*-2(2substituted phenyl) derivant of - 4-methoxy-1,3-benzol diamide and use of the same | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-07 | — | — | CN | disclosed |