Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799322 | 0.80 | MEN1 (0.36) | MEN1KMT2ATP53FFAR1FFAR4 | |
| SCHEMBL10975508 | 0.72 | ESR1 (0.35) | TP53THRBBCHE | |
| SCHEMBL27686272 | 0.69 | SMN1; SMN2 (0.39) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL27686308 | 0.68 | PDK2 (0.36) | MEN1KMT2AMAPTFFAR1FFAR4 | |
| SCHEMBL6504472 | 0.66 | MAPK14 (0.48) | MAPTSMN1; SMN2HPGDRXRARXRB | |
| SCHEMBL28567295 | 0.66 | TP53 (0.35) | TP53POLBGAAMAPTHPGD | |
| SCHEMBL21647153 | 0.65 | LMNA (0.44) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL4130095 | 0.64 | MAPT (0.59) | STAT3MAPTFFAR4SMN1; SMN2HDAC6 | |
| SCHEMBL990720 | 0.64 | KMT2A (0.69) | MEN1KMT2ATP53TDP1 | |
| SCHEMBL10799286 | 0.63 | GPR84 (0.34) | FFAR1FFAR4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955470-A | Glutamate receptor potentiators | LILLY CO ELI | 2011-01-26 | — | — | CN | disclosed |
| CN-101061106-B | Glutamate receptor potentiators | LILLY CO ELI | 2010-09-29 | — | — | CN | disclosed |
| CN-101061106-A | Glutamate receptor potentiators | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |