Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705388 | 0.91 | SORT1 (0.38) | IL2SORT1RAB9ANPC1ALOX15 | |
| SCHEMBL15395956 | 0.74 | KDM4E (0.47) | IL2RAB9ANPC1TP53MITF | |
| SCHEMBL5554369 | 0.74 | IL2 (0.51) | IL2RAB9A | |
| SCHEMBL15395772 | 0.74 | IL2 (0.55) | IL2RAB9ANPC1 | |
| SCHEMBL5550650 | 0.73 | ORAI1 (0.52) | IL2RAB9ANPC1TP53MITF | |
| SCHEMBL5550506 | 0.73 | IL2 (0.44) | IL2SORT1RAB9ANPC1TP53 | |
| SCHEMBL5554305 | 0.73 | IL2 (0.44) | IL2RAB9ANPC1TP53POLQ | |
| SCHEMBL5555293 | 0.73 | IL2 (0.51) | IL2 | |
| SCHEMBL5998369 | 0.72 | IL2 (0.45) | IL2RAB9ANPC1TP53GAA | |
| SCHEMBL8260575 | 0.71 | IL2 (0.48) | IL2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163478-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2008-04-16 | — | — | CN | claimed |
| CN-101163478-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2008-04-16 | — | — | CN | disclosed |