Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uracil SCHEMBL151239 | 0.86 | — | — | |
| Uracil SCHEMBL27271010 | 0.84 | — | — | |
| Uracil SCHEMBL5182388 | 0.84 | — | — | |
| Uracil SCHEMBL28745089 | 0.84 | — | — | |
| Uracil SCHEMBL15456754 | 0.82 | KDM4E (0.34) | ALDH1A1KDM4ERAB9ASMN1; SMN2MEN1 | |
| Uracil SCHEMBL28028641 | 0.78 | HSP90AA1 (0.32) | HSP90AA1 | |
| Uracil SCHEMBL5125135 | 0.78 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAB9ASMN1; SMN2MEN1 | |
| SCHEMBL592929 | 0.78 | ADORA2A (0.64) | AURKAHSP90AA1PRKACAADORA2AKDM4E | |
| SCHEMBL1163789 | 0.78 | NPC1 (0.49) | AURKAHSP90AA1PRKACAADORA2AKDM4E | |
| Bromide SCHEMBL30271836 | 0.77 | NPC1 (0.47) | ADORA2AKDM4ENPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101182310-B | Method for preparing biphenyl substituted pyrimidine compounds | UNIV EAST CHINA SCIENCE & TECH | 2010-04-14 | — | — | CN | disclosed |
| CN-101182310-A | Method for preparing biphenyl substituted pyrimidine compounds | UNIV EAST CHINA SCIENCE & TECH (CN) | 2008-05-21 | — | — | CN | disclosed |