Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30271836 | 0.98 | NPC1 (0.47) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL2679197 | 0.83 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL27877200 | 0.80 | CYP2A6 (0.62) | KMT2AMAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL29049464 | 0.79 | NPC1 (0.40) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL30525575 | 0.79 | NPC1 (0.40) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL2556630 | 0.79 | MEN1 (0.66) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL28759232 | 0.79 | HSD17B1 (0.42) | NPC1RAB9AKMT2AMEN1MAPT | |
| Biphenyl SCHEMBL27705553 | 0.78 | AURKA (0.44) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30271753 | 0.77 | CYP19A1 (0.51) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL27887540 | 0.77 | PDE4A (0.40) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832624-B1 | Use of cerium dioxide for the stabilization of organic polymers against free radicals | BYK CHEMIE GMBH (DE) | 2009-05-13 | — | — | EP | claimed |
| EP-1832624-A1 | Stabilization of organic polymers against free radicals | Byk-Chemie GmbH (DE) | 2007-09-12 | — | — | EP | claimed |
| US-20060073280-A1 | Method for producing uv abbsorption layers on substrates | BAUER MICHAEL | 2006-04-06 | — | — | US | claimed |
| EP-1304351-B1 | Uv stabilized, impact modified polyester/polycarbonate blends | GEN ELECTRIC (US) | 2006-01-04 | — | — | EP | claimed |
| CN-1703287-A | Method for forming UV-absorbing layer on substrate | CIBA SC HOLDING AG (CH) | 2005-11-30 | — | — | CN | claimed |
| EP-1558402-A2 | METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES | Ciba Specialty Chemicals Holding Inc. (CH) | 2005-08-03 | — | — | EP | claimed |
| WO-2004035667-A2 | METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-29 | — | — | WO | claimed |
| US-6630527-B2 | Cycloaliphatic polyester resin and a linear polycarbonate resin; a rubber grafted ABS impact modifier; an additive composition, comprising a hindered amine light stabilizer | GENERAL ELECTRIC COMPANY | 2003-10-07 | — | — | US | claimed |
| US-20030109629-A1 | UV stabilized, impact modified polyester/polycarbonate blends, articles, and methods of manufacture thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2003-06-12 | — | — | US | claimed |
| EP-1304351-A1 | Uv stabilized, impact modified polyester/polycarbonate blends | GENERAL ELECTRIC COMPANY (US) | 2003-04-23 | — | — | EP | claimed |
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | claimed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| JP-6135939-A | — | — | None | — | — | JP | disclosed |
| JP-6009503-A | — | — | None | — | — | JP | disclosed |
| JP-9048760-A | — | — | None | — | — | JP | disclosed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0215235-A1 | Phosphoric acid esters | BAYER AG (DE) | 1987-03-25 | — | — | EP | disclosed |
| EP-0061588-A1 | Process for the chlorination of cyclic amides and cyclic vinylogous amides | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-10-06 | — | — | EP | disclosed |