Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29337963 | 0.85 | HTR6 (0.50) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL10179635 | 0.81 | HTR6 (0.54) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL10192332 | 0.77 | HDAC4 (0.54) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL27870611 | 0.75 | PTGS2 (0.57) | HTR6SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL11300578 | 0.75 | SMN1; SMN2 (0.52) | HTR6SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL27705670 | 0.74 | SMN1; SMN2 (0.45) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL1882668 | 0.74 | SMN1; SMN2 (0.45) | HTR6SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL198507 | 0.74 | TSHR (0.52) | ALDH1A1MAPTPOLBLMNATSHR | |
| SCHEMBL28208618 | 0.74 | TSHR (0.52) | ALDH1A1MAPTPOLBLMNATSHR | |
| SCHEMBL7039581 | 0.74 | TSHR (0.52) | ALDH1A1MAPTPOLBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101184726-B | 2-arylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG | 2012-05-30 | — | — | CN | disclosed |
| CN-101184726-A | 2-arylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG (IT) | 2008-05-21 | — | — | CN | disclosed |