Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 14/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.40 |
| ▸ | GABRP | O00591 | 9/20 | 0.40 |
| ▸ | GABRD | O14764 | 9/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.40 |
| ▸ | GABRE | P78334 | 9/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345400 | 0.90 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9010458 | 0.90 | GABRB3 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2773006 | 0.87 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL3970589 | 0.86 | GABRB3 (0.45) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14648752 | 0.84 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6793299 | 0.84 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL11914603 | 0.83 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14648759 | 0.83 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL28913303 | 0.83 | GABRP (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL11914602 | 0.82 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812347-B2 | ALKYLATING SECONDARY AMIDE GROUP OF SUCH AS 1-(2,6-DICHLORO-4-TRIFLUOROMETHYLPHENYL)-3-CYANO-4-TRIFLUOROMETHYLSULFINYL-5-(ETHOXYACETAMIDO)PYRAZOLE; BYPRODUCT INHIBITION; ELIMINATES FINAL PURIFICATION STEP | BAYER CROPSCIENCE S.A. (FR) | 2004-11-02 | — | — | US | claimed |
| US-8362086-B2 | Long acting injectable formulations | MERIAL LIMITED (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362086-B2 | Long acting injectable formulations | MERIAL LIMITED (US) | 2013-01-29 | — | — | US | disclosed |
| EP-1286970-B1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS AND NOVEL INTERMEDIATES THEREOF | MERIAL LTD (US) | 2010-04-28 | — | — | EP | disclosed |
| US-20070042013-A1 | Long acting injectable formulations | MERIAL, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070042013-A1 | Long acting injectable formulations | MERIAL, INC. | 2007-02-22 | — | — | US | disclosed |
| US-6812347-B2 | ALKYLATING SECONDARY AMIDE GROUP OF SUCH AS 1-(2,6-DICHLORO-4-TRIFLUOROMETHYLPHENYL)-3-CYANO-4-TRIFLUOROMETHYLSULFINYL-5-(ETHOXYACETAMIDO)PYRAZOLE; BYPRODUCT INHIBITION; ELIMINATES FINAL PURIFICATION STEP | BAYER CROPSCIENCE S.A. (FR) | 2004-11-02 | — | — | US | disclosed |
| US-20030166940-A1 | Processes for the preparation of pesticidal compounds and novel intermediates thereof | MERIAL, INC. | 2003-09-04 | — | — | US | disclosed |
| EP-1286970-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS AND NOVEL INTERMEDIATES THEREOF | AVENTIS CROPSCIENCE S.A. (FR) | 2003-03-05 | — | — | EP | disclosed |
| EP-1223165-A1 | Processes for the preparation of pesticidal compound | AVENTIS CROPSCIENCE S.A. (FR) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001094316-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS AND NOVEL INTERMEDIATES THEREOF | BAYER CROPSCIENCE S.A. (FR) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042013-A1 | Long acting injectable formulations | LPXN, VIP, VEGFA | GABRB3 3327/4885GABRA2 2436/4885GABRB2 3342/4885 |
| US-20030166940-A1 | Processes for the preparation of pesticidal compounds and novel intermediates thereof | DDT, KCNH1, HCN4 | GABRB3 3169/4885GABRA2 3577/4885GABRB2 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.