Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL3181225 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2485076 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8641217 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5480105 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8646850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL669850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL9070382 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8644290 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5469158 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL706277 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737095-B2 | Hydrodynamic bearing device, and spindle motor and information device using the same | PANASONIC CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20060171613-A1 | Hydrodynamic bearing device, and spindle motor and information device using the same | PHC HOLDINGS CO., LTD. (JP) | 2006-08-03 | — | — | US | disclosed |