Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL3181225 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2485076 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8641217 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5480105 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8646850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL669850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2770664 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL9070382 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8644290 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5469158 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160051456-A1 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | DEB IP LIMITED (GB) | 2016-02-25 | — | — | US | claimed |
| EP-2234577-A2 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | Evonik Goldschmidt GmbH (DE) | 2010-10-06 | — | — | EP | claimed |
| WO-2009095351-A2 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-08-06 | — | — | WO | claimed |
| US-20090191285-A1 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | EVONIK DEGUSSA CORPORATION (US) | 2009-07-30 | — | — | US | claimed |
| WO-2026102252-A1 | COMPOSITION AND METHOD FOR MODULATING MICROBIOMES WITH POSTBIOTIC FERMENTS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| WO-2026102269-A1 | HYPOGRAVITY PREPARATION OF POSTBIOTIC FERMENTS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260114445-A1 | STABLE ANTIMICROBIAL FORMULATION CONCENTRATE | KIMBERLY CLARK CO (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260021219-A1 | METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY | KIMBERLY CLARK CO (US) | 2026-01-22 | — | — | US | disclosed |
| US-12486996-B2 | Antimicrobial composition including an acyl lactylate and a glycol and methods of inhibiting microbial growth utilizing the same | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| EP-4013378-B1 | WETTING COMPOSITION INCLUDING SILICONE POLYMER SOFTENING AGENT AND WET WIPES INCLUDING THE SAME | KIMBERLY CLARK CO (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120018853-A | Methods and absorbent articles for inhibiting fecal protease activity | 金伯利-克拉克环球有限公司 | 2025-05-16 | — | — | CN | disclosed |
| US-12295365-B2 | Composition including an antimicrobial boosting agent including a sultaine and methods of increasing the antimicrobial effectiveness of a composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2025-05-13 | — | — | US | disclosed |
| US-6149934-A | LOTION FORMULATION ACTS AS A LUBRICANT TO REDUCEABRASION OF THE SKIN CAUSED BY LINER AND ALSO TRANSFERS TO THE SKIN TO PROVIDE IMPROVED SKIN HEALTH; FOR DISPOSABLE PRODUCTS SUCH AS DIAPERS, INCONTINENCE PRODUCTS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| WO-2000064502-A1 | ABSORBENT ARTICLE HAVING A LOTIONIZED BODYSIDE LINER | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| CN-1253493-A | Skin care compositions containing combinations of compounds for mimicking effect on skin of retinoic acid | UNILEVER PLC (NL) | 2000-05-17 | — | — | CN | disclosed |
| WO-2000026285-A1 | GEL COMPOSITIONS | PENRECO (US) | 2000-05-11 | — | — | WO | disclosed |
| CN-1231173-A | Cosmetic skin or hair care compositions containing fluorocarbons infused with carbon dioxide | UNILEVER NV (NL) | 1999-10-13 | — | — | CN | disclosed |
| CN-1176783-A | Borage seed oil as anti-irritant in compositions containing hydroxy acids or retinoids | UNILEVER NV (NL) | 1998-03-25 | — | — | CN | disclosed |
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | disclosed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021219-A1 | METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY | CUTA, CTRL, PEPD | USP2 369/4885HTT 4053/4885MEN1 2930/4885 |
| US-12295365-B2 | Composition including an antimicrobial boosting agent including a sultaine and methods of increasing the antimicrobial effectiveness of a composition | SULT1A1, MGAM, IFNG | USP2 3032/4885HTT 2912/4885MEN1 2257/4885 |
| US-20260114445-A1 | STABLE ANTIMICROBIAL FORMULATION CONCENTRATE | CUTA, SUCLG1, SORD | USP2 3294/4885HTT 1627/4885MEN1 4202/4885 |
| US-20090191285-A1 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | CUTA, LCT, AQP1 | USP2 2434/4885HTT 2261/4885MEN1 2469/4885 |
| US-20160051456-A1 | MOISTURIZING LIQUID LINER FOR BARRIER LAYER | CUTA, LCT, AQP1 | USP2 2434/4885HTT 2261/4885MEN1 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.