Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL3181225 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2485076 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8641217 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5480105 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8646850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2770664 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL9070382 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8644290 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5469158 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL706277 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091324-A2 | ANTIMICROBIAL COMPOSITIONS | 3M Innovative Properties Company (US) | 2009-08-26 | — | — | EP | claimed |
| CN-100469367-C | Transdermal preparations comprising eperisone, tolperisone or salts thereof | AMOREPACIFIC CORP (KR) | 2009-03-18 | — | — | CN | claimed |
| WO-2008057773-A2 | ANTIMICROBIAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-05-15 | — | — | WO | claimed |
| CN-1703219-A | Transdermal preparations comprising eperisone, tolperisone or salts thereof | AMOREPACIFIC CORP (KR) | 2005-11-30 | — | — | CN | claimed |
| CN-115777706-A | Concentrated quaternary ammonium salt disinfectant for oral cavity pipeline and preparation method thereof | 山东宏润空压机科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-113260333-A | Antimicrobial dental appliance | 3M创新有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-108064203-B | Sequentially peelable coextruded polymeric films with embedded antimicrobial layers | 3M创新有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-20200188286-A1 | CLEANSING HAIR OIL, METHOD FOR APPLYING SAME, AND USE OF SAME FOR CARE OF KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2020-06-18 | — | — | US | disclosed |
| EP-2091324-B1 | ANTIMICROBIAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2016-12-28 | — | — | EP | disclosed |
| US-8623935-B2 | Antimicrobial compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-01-07 | — | — | US | disclosed |
| US-8569384-B2 | Antimicrobial compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-29 | — | — | US | disclosed |
| EP-2240031-B1 | ANTIMICROBIAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
| EP-1113784-A1 | USE OF ISOPARAFFIN EXTENDERS FOR CLEAR GEL COSMETIC COMPOSITIONS | ExxonMobil Chemical Patents Inc. (US) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015191-A1 | USE OF ISOPARAFFIN EXTENDERS FOR CLEAR GEL COSMETIC COMPOSITIONS | EXXON CHEMICAL PATENTS INC. (US) | 2000-03-23 | — | — | WO | disclosed |
| US-6040367-A | EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2000-03-21 | — | — | US | disclosed |
| US-5977206-A | Polycarbonate resin composition | MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5948838-A | 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT | MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0794218-A2 | Polycarbonate resin composition stabilized against radiation | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0753540-A2 | Polycarbonate resin composition | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 1997-01-15 | — | — | EP | disclosed |