Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NMT1 | P30419 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719507 | 0.85 | SPHK1 (0.40) | KDM4EALDH1A1NMT1FAAHGPR119 | |
| SCHEMBL27687895 | 0.85 | CHRM3 (0.42) | CHRM3NMT1FAAHGPR119 | |
| SCHEMBL28769798 | 0.83 | CYP19A1 (0.36) | NAMPTALDH1A1CHRM3CYP19A1ACHE | |
| SCHEMBL27719496 | 0.82 | GPR119 (0.53) | NMT1GPR119 | |
| SCHEMBL27740583 | 0.82 | MAOA (0.46) | ACHEGPR119 | |
| SCHEMBL27687968 | 0.82 | FAAH (0.44) | ACHEFAAH | |
| SCHEMBL27707133 | 0.82 | CYP19A1 (0.42) | NAMPTALDH1A1CYP19A1ACHE | |
| SCHEMBL389218 | 0.82 | GPR119 (0.54) | KDM4EFAAHGPR119 | |
| SCHEMBL27707144 | 0.81 | CHRM3 (0.36) | NAMPTKDM4EALDH1A1CHRM3CYP19A1 | |
| SCHEMBL27740578 | 0.81 | NMT1 (0.37) | KDM4EALDH1A1NMT1GPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101123964-B | G-protein coupled receptor (GPR116) agonists and pharmaceutical compositions comprising the same | PROSIDION LTD | 2012-11-28 | — | — | CN | disclosed |
| CN-101123964-A | G-protein coupled receptor (GPR116) agonists and their use for the treatment of obesity and diabetes | PROSIDION LTD (GB) | 2008-02-13 | — | — | CN | disclosed |