Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584959 | 0.83 | HSD17B10 (0.55) | KMT2ASMN1; SMN2MAPK1RAB9AKDM4E | |
| SCHEMBL6473755 | 0.77 | KDM4C (0.75) | KMT2AKDM4CPARP1MAOBTNKS2 | |
| SCHEMBL28503293 | 0.73 | PARP1 (0.59) | KMT2AKDM4CPARP1MAOBPARP2 | |
| SCHEMBL148952 | 0.72 | TNKS2 (0.61) | PARP1TNKS2QTRT1RAB9ATNKS | |
| SCHEMBL31070299 | 0.72 | TNKS2 (0.61) | PARP1TNKS2QTRT1RAB9ATNKS | |
| SCHEMBL28502323 | 0.71 | HCAR2 (0.53) | KMT2AKDM4CPARP1MAOBPARP2 | |
| Hydrochloric Acid SCHEMBL15709417 | 0.71 | TNKS2 (0.59) | PARP1TNKS2QTRT1RAB9ATNKS | |
| Hydrochloric Acid SCHEMBL15742407 | 0.71 | KDM4C (0.65) | KMT2AKDM4CPARP1TNKS2QTRT1 | |
| SCHEMBL3558037 | 0.70 | KDM4E (0.66) | KMT2APARP1PARP2TNKS2SMN1; SMN2 | |
| SCHEMBL27729998 | 0.70 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MAPK1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208094-B | Pharmacokinetic improved compounds | SURFACE LOGIX, INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-101208094-A | Pharmacokinetic improved compounds | SURFACE LOGIX INC (US) | 2008-06-25 | — | — | CN | disclosed |