Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.47 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28502323 | 0.84 | HCAR2 (0.53) | PARP1PARP2HCAR2KDM4CRAB9A | |
| SCHEMBL6886533 | 0.82 | TNKS2 (0.56) | PARP1HCAR2KDM4CRAB9AMAOB | |
| SCHEMBL6004217 | 0.81 | TNKS2 (0.51) | PARP1HCAR2KDM4CRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL15742407 | 0.78 | KDM4C (0.65) | PARP1KDM4CRAB9ATNKS2QTRT1 | |
| SCHEMBL6473755 | 0.78 | KDM4C (0.75) | PARP1HCAR2KDM4CRAB9AMAOB | |
| SCHEMBL23068618 | 0.76 | PARP1 (0.59) | PARP1PARP2TNKS2TNKS | |
| SCHEMBL6597891 | 0.76 | ACHE (0.48) | PARP1HCAR2KDM4CRAB9AMAOB | |
| SCHEMBL2718160 | 0.75 | PARP1 (1.00) | PARP1PARP2MAPTTNKS2KMT2A | |
| SCHEMBL29903052 | 0.75 | PARP1 (1.00) | PARP1PARP2MAPTTNKS2KMT2A | |
| SCHEMBL38651228 | 0.74 | HTR3A (0.56) | PARP1PARP2MAPTTNKS2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226808-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |