Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810074 | 0.76 | MAPT (0.49) | SMN1; SMN2CYP19A1KDM4EGLAMEN1 | |
| SCHEMBL1012732 | 0.74 | PIN1 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1TSHRHTT | |
| SCHEMBL27709478 | 0.70 | KMT2A (0.51) | SMN1; SMN2KDM4ELMNAPOLBGAA | |
| SCHEMBL28195451 | 0.70 | CYP19A1 (0.48) | SMN1; SMN2CYP19A1KDM4EGLAMEN1 | |
| SCHEMBL3290432 | 0.68 | HSD17B10 (0.56) | SMN1; SMN2KDM4EMEN1LMNAGAA | |
| Bicarbonate SCHEMBL11023181 | 0.68 | MAOA (0.48) | SMN1; SMN2KDM4EGLAMEN1GAA | |
| SCHEMBL11806239 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP19A1KDM4EGLAMEN1 | |
| SCHEMBL11783599 | 0.67 | KMT2A (0.61) | SMN1; SMN2CYP19A1MEN1MAPTKMT2A | |
| SCHEMBL10573912 | 0.67 | MAPK1 (0.61) | SMN1; SMN2CYP19A1KMT2AALDH1A1MAPK1 | |
| SCHEMBL538524 | 0.67 | CYP19A1 (0.76) | SMN1; SMN2CYP19A1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208094-B | Pharmacokinetic improved compounds | SURFACE LOGIX, INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-101208094-A | Pharmacokinetic improved compounds | SURFACE LOGIX INC (US) | 2008-06-25 | — | — | CN | disclosed |