Cystine

SCHEMBL9667231

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CSSC[C@H](N)C(=O)O)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARD PTGS1 PTGS2 dacA dacB dacC ftsI mrcA mrcB mrdA

The experimentally established mechanism targets of Cystine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.32

▸	GLP1R	P43220	6/20	0.30

▸	CRHR1	P34998	1/20	0.30

▸	CRHR2	Q13324	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Cystine SCHEMBL9667228	1.00	CALCR (0.32)	CALCRGLP1RCRHR1CRHR2
D-Histidine SCHEMBL27900898	0.88	BACE1 (0.33)	CALCRCRHR1CRHR2
Arginine SCHEMBL6481630	0.88	GLP1R (0.35)	GLP1R
Cystine SCHEMBL27709554	0.86	GLP1R (0.32)	GLP1R
Histidine SCHEMBL27716140	0.86	ALOX15 (0.33)	—
Arginine SCHEMBL27611401	0.85	PTH1R (0.36)	CALCRGLP1R
Phenylalanine SCHEMBL28079153	0.85	BACE1 (0.36)	CALCRGLP1RCRHR1CRHR2
Arginine SCHEMBL27629650	0.85	GLP1R (0.34)	GLP1R
Histidine SCHEMBL28540445	0.85	THRB (0.34)	—
Dl-Phenylalanine SCHEMBL27667772	0.85	THRB (0.34)	CALCRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0506923-A1	A COLLAGEN BINDING PROTEIN AS WELL AS ITS PREPARATION.	ALFA LAVAL AGRI INT (SE)	1992-10-07	—	—	EP	disclosed
WO-1992007002-A1	A COLLAGEN BINDING PROTEIN AS WELL AS ITS PREPARATION	ALFA-LAVAL AGRI INTERNATIONAL AKTIEBOLAG (SE)	1992-04-30	—	—	WO	disclosed