Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723024 | 0.76 | EPHX1 (0.40) | L3MBTL1HTTEPHX1 | |
| SCHEMBL27710943 | 0.75 | L3MBTL1 (0.40) | L3MBTL1FFAR2HTTPIN1APEX1 | |
| SCHEMBL29979933 | 0.72 | TACR1 (0.42) | L3MBTL1FFAR2PIN1ALDH1A1 | |
| SCHEMBL27738471 | 0.72 | HPGD (0.56) | ALDH1A1TSHREPHX1 | |
| SCHEMBL27600068 | 0.70 | EPHX1 (0.71) | EPHX1 | |
| SCHEMBL1449520 | 0.69 | HTT (0.65) | L3MBTL1HTTPIN1ALDH1A1CA12 | |
| SCHEMBL16017456 | 0.68 | PIN1 (0.42) | L3MBTL1FFAR2HTTPIN1KEAP1 | |
| SCHEMBL27558033 | 0.68 | CYP2C19 (0.47) | ALDH1A1EPHX1 | |
| SCHEMBL27511043 | 0.67 | CHRM1 (0.61) | HTTALDH1A1TSHREPHX1 | |
| SCHEMBL4935067 | 0.66 | LMNA (0.61) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061115-A | 2-acylaminothiazole derivatives | LUNDBECK & CO AS H (DK) | 2007-10-24 | — | — | CN | disclosed |