Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711176 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EPOLBMEN1 | |
| SCHEMBL27731762 | 0.83 | GAA (0.47) | ALDH1A1HPGDKDM4EPOLBMEN1 | |
| SCHEMBL27711185 | 0.83 | GAA (0.47) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL5180569 | 0.79 | GAA (0.48) | ALDH1A1HPGDKDM4ESMN1; SMN2GAA | |
| SCHEMBL27731804 | 0.79 | HCAR3 (0.47) | ALDH1A1POLBKMT2ASMN1; SMN2GAA | |
| SCHEMBL27731721 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL27711220 | 0.77 | GAA (0.42) | ALDH1A1HPGDKDM4ESMN1; SMN2GAA | |
| SCHEMBL27711219 | 0.76 | KDM4E (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL27731887 | 0.74 | MAOB (0.49) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12983141 | 0.72 | MEN1 (0.55) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |