Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731867 | 0.86 | ELANE (0.39) | GAAALDH1A1ELANEPRTN3SMN1; SMN2 | |
| SCHEMBL27711287 | 0.85 | ALDH1A1 (0.45) | GAAALDH1A1ELANEPRTN3SMN1; SMN2 | |
| SCHEMBL27731903 | 0.84 | GAA (0.42) | GAAALDH1A1SMN1; SMN2PKMENPP3 | |
| SCHEMBL27711215 | 0.82 | ELANE (0.39) | GAAALDH1A1ELANEPRTN3SMN1; SMN2 | |
| SCHEMBL27731790 | 0.80 | CISD1 (0.42) | GAAALDH1A1ELANEPRTN3SMN1; SMN2 | |
| SCHEMBL27711281 | 0.79 | KDM4E (0.46) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL27731887 | 0.78 | MAOB (0.49) | GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27711183 | 0.77 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL27711185 | 0.77 | GAA (0.47) | GAAALDH1A1SMN1; SMN2HCAR3HSP90AB1 | |
| SCHEMBL27731762 | 0.77 | GAA (0.47) | GAAALDH1A1SMN1; SMN2HCAR3HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |