Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711215 | 0.87 | ELANE (0.39) | ELANEPRTN3ALDH1A1KDM4EHSP90AB1 | |
| SCHEMBL27711220 | 0.86 | GAA (0.42) | ELANEPRTN3ALDH1A1KDM4EHSP90AB1 | |
| SCHEMBL27731790 | 0.85 | CISD1 (0.42) | ELANEPRTN3ALDH1A1KDM4EMKNK2 | |
| SCHEMBL27711281 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4EMAPT | |
| SCHEMBL27711256 | 0.83 | SMN1; SMN2 (0.46) | ELANEPRTN3ALDH1A1POLBENPP3 | |
| SCHEMBL27711267 | 0.82 | KMT2A (0.46) | ELANEPRTN3ALDH1A1ENPP3ENPP1 | |
| SCHEMBL27711170 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSP90AB1HMGCRPPARG | |
| SCHEMBL10923492 | 0.74 | KDM4E (0.45) | ALDH1A1KDM4EENPP3ENPP1HPGD | |
| SCHEMBL27731760 | 0.73 | STAT3 (0.46) | ALDH1A1KDM4EHSP90AB1POLBMKNK1 | |
| SCHEMBL27731803 | 0.73 | HSP90AB1 (0.42) | ALDH1A1KDM4EHSP90AB1POLBMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |