SCHEMBL27712430

SCHEMBL27712430

Cc1cnc(C#CCO)c(C)n1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
GRM5 P41594 1/20 0.35
JAK3 P52333 1/20 0.34
MELK Q14680 1/20 0.33
PGK1 P00558 1/20 0.33
AKT1 P31749 1/20 0.32
ROCK1 Q13464 1/20 0.32
RPS6KA1 Q15418 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7576503 0.71 KDM4E (0.34) ALDH1A1HTTGRM5JAK3
SCHEMBL8560673 0.71 JAK3 (0.34) JAK3
SCHEMBL739723 0.70 ALDH1A1 (0.43) ALDH1A1GAAHTTGRM5AKT1
Alcohol SCHEMBL28121239 0.69 JAK3 (0.39) ALDH1A1JAK3
SCHEMBL15211469 0.67 ALDH1A1 (0.42) ALDH1A1JAK3
SCHEMBL17522878 0.67 ALDH1A1 (0.36) ALDH1A1GAAHTTGRM5MELK
SCHEMBL4281580 0.65 CYP2A6 (0.66) ALDH1A1GRM5MELK
Methyl Alcohol SCHEMBL16458351 0.65 JAK3 (0.42) ALDH1A1GRM5JAK3
SCHEMBL9088542 0.64 ALDH1A1 (0.36) ALDH1A1GAAHTTMELKPGK1
SCHEMBL27712286 0.64 NOS2 (0.39) ALDH1A1GAAHTTMELK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101111499-B Substituted ethynyl gold-nitrogen-containing heterocyclic carbene complex and organic electroluminescent device using the same UBE INDUSTRIES 2012-05-23 CN disclosed
CN-101111499-A Substituted ethynyl gold-nitrogenated heterocyclic carbene complex and organic electroluminescent device using same UBE INDUSTRIES (JP) 2008-01-23 CN disclosed