SCHEMBL2771250

SCHEMBL2771250

Cc1[nH]c2c(N3CCc4cc(F)ccc4C3C)cncc2c1C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCD O00767 3/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2768910 0.99 SCD (0.32) SCDTRPA1ALDH1A1SMN1; SMN2
SCHEMBL3592872 0.80 ROCK1 (0.34) SCDTRPA1ALDH1A1SMN1; SMN2NOTUM
SCHEMBL1737805 0.79 CCNB2 (0.34) SCDALDH1A1SMN1; SMN2
SCHEMBL1739177 0.78 CCNB2 (0.33) SCDALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL1735825 0.78 CCNB2 (0.33) SCDALDH1A1SMN1; SMN2
SCHEMBL1739182 0.78 CCNB2 (0.33) SCDALDH1A1SMN1; SMN2
SCHEMBL1737475 0.71 HTR2A (0.35) SCDALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL1736669 0.70 HTR2A (0.34) SCDALDH1A1
SCHEMBL2769090 0.69 RAB9A (0.39) ALDH1A1NOTUM
SCHEMBL3578625 0.67 RAB9A (0.39) ALDH1A1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1805177-B9 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2010-09-15 EP claimed
EP-1805177-B1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2010-04-28 EP claimed