Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578625 | 0.92 | RAB9A (0.39) | RAB9AHTTALDH1A1MAPTTDP1 | |
| SCHEMBL1736577 | 0.79 | MAPT (0.50) | RAB9AHTTALDH1A1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL27546424 | 0.73 | MC4R (0.38) | CYP11B1MTNR1B | |
| SCHEMBL7837598 | 0.70 | KDM4E (0.39) | ALDH1A1HTR2ANOTUMMTNR1B | |
| SCHEMBL27901787 | 0.70 | CYP11B2 (0.35) | GAACYP11B1NOTUMMTNR1B | |
| SCHEMBL1737670 | 0.70 | MAPT (0.50) | RAB9AALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL2771250 | 0.69 | SCD (0.32) | ALDH1A1NOTUM | |
| SCHEMBL27901781 | 0.69 | MAPT (0.35) | RAB9AHTTALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL2768910 | 0.69 | SCD (0.32) | ALDH1A1 | |
| SCHEMBL27919506 | 0.67 | CYP17A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805177-B9 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-09-15 | — | — | EP | disclosed |
| EP-1805177-B1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-04-28 | — | — | EP | disclosed |
| EP-1805177-A4 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-07-29 | — | — | EP | disclosed |
| US-7541366-B2 | Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2009-06-02 | — | — | US | disclosed |
| US-20070249658-A1 | Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof | YUHAN CORPORATION (KR) | 2007-10-25 | — | — | US | disclosed |
| EP-1805177-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006025715-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249658-A1 | Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof | ATP6AP1, HPD, ATP6V1H | RAB9A 240/4885HTT 567/4885ALDH1A1 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.