Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221339 | 0.89 | NOTUM (0.54) | NOTUMAKR1C3AKR1C1KDM4ESMN1; SMN2 | |
| SCHEMBL31073529 | 0.81 | NOTUM (0.53) | NOTUMAKR1C3AKR1C1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16205305 | 0.81 | NOTUM (0.47) | NOTUMAKR1C3AKR1C1KDM4ESMN1; SMN2 | |
| SCHEMBL3104046 | 0.81 | L3MBTL1 (0.45) | NOTUMALDH1A1NPSR1KDM4EL3MBTL1 | |
| SCHEMBL34462085 | 0.79 | NOTUM (0.46) | NOTUMALDH1A1NPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3347621 | 0.78 | ELANE (0.54) | ELANEPOLB | |
| SCHEMBL2172636 | 0.78 | ELANE (0.54) | ELANEPOLB | |
| SCHEMBL15665470 | 0.78 | ELANE (0.54) | ELANEPOLB | |
| SCHEMBL5702089 | 0.77 | NOTUM (0.49) | NOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL5702158 | 0.77 | NOTUM (0.49) | NOTUMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107218-A | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-01-16 | — | — | CN | claimed |
| CN-101107218-A | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-01-16 | — | — | CN | disclosed |