Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103862 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29159295 | 0.74 | MAPT (0.31) | ALDH1A1HPGDHSD17B10KMT2ACYP1A2 | |
| SCHEMBL27713184 | 0.73 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL4442087 | 0.70 | L3MBTL1 (0.34) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL14638813 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Glycerin SCHEMBL4438885 | 0.68 | DHFR (0.36) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL737754 | 0.66 | CYP1A2 (0.42) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2036514 | 0.66 | APP (0.44) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28592799 | 0.64 | CYP1A2 (0.48) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28287439 | 0.62 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101238213-A | Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of tina | TINA HOLDING APS (DK) | 2008-08-06 | — | — | CN | disclosed |