Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733781 | 0.88 | KLK7 (0.47) | HTR6HTR7MEN1KMT2ALMNA | |
| SCHEMBL27713327 | 0.87 | MEN1 (0.43) | HTR6HTR7PTGDR2MEN1KMT2A | |
| SCHEMBL27713331 | 0.87 | HTR6 (0.48) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27713443 | 0.87 | AKR1C3 (0.48) | HTR6HTR7MEN1KMT2ALMNA | |
| SCHEMBL28770869 | 0.86 | LMNA (0.56) | HTR6HTR7MEN1KMT2ALMNA | |
| SCHEMBL27713312 | 0.86 | SMN1; SMN2 (0.49) | HTR6HTR7MEN1KMT2ALMNA | |
| SCHEMBL27733689 | 0.85 | ELANE (0.47) | HTR6HTR7MEN1KMT2ALMNA | |
| SCHEMBL27733870 | 0.84 | PPARG (0.52) | HTR6HTR2AHTR7MEN1KMT2A | |
| SCHEMBL27713295 | 0.84 | KMT2A (0.40) | HTR6HTR2AMEN1KMT2ALMNA | |
| SCHEMBL27733649 | 0.83 | HTR6 (0.42) | HTR6MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |