Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 9/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713312 | 0.90 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27733781 | 0.86 | KLK7 (0.47) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27713337 | 0.85 | HTR6 (0.48) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27713443 | 0.85 | AKR1C3 (0.48) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27713331 | 0.85 | HTR6 (0.48) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL28770869 | 0.84 | LMNA (0.56) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27713327 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27733870 | 0.81 | PPARG (0.52) | MEN1KMT2ASMN1; SMN2LMNAHTR6 | |
| SCHEMBL27733649 | 0.80 | HTR6 (0.42) | MEN1KMT2ASMN1; SMN2LMNAPLK1 | |
| SCHEMBL27713295 | 0.78 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2LMNAPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |