Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | USP5 | P45974 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493552 | 0.89 | MMP3 (0.46) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2154896 | 0.88 | MMP3 (0.48) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5506459 | 0.85 | MMP3 (0.43) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2155207 | 0.83 | MMP3 (0.46) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27693773 | 0.80 | USP5 (0.38) | MMP3USP5KDM4EALDH1A1NPC1 | |
| SCHEMBL2154893 | 0.80 | MMP3 (0.39) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2156536 | 0.78 | MMP3 (0.51) | MMP3USP5KDM4EALDH1A1RAB9A | |
| SCHEMBL5509222 | 0.77 | MMP3 (0.50) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2156697 | 0.75 | MMP3 (0.44) | MMP3USP5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27693768 | 0.73 | MAPT (0.47) | ALDH1A1SMN1; SMN2NPC1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |