Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 5/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770838 | 0.89 | ALDH1A1 (0.35) | ALDH1A1GAAMAPTTSHRPPARG | |
| SCHEMBL28775106 | 0.85 | TRPV1 (0.34) | MAPTPPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL27713464 | 0.84 | NOTUM (0.47) | ALDH1A1GAAMAPTTSHR | |
| SCHEMBL27833814 | 0.82 | PPARG (0.37) | ALDH1A1PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL27813772 | 0.81 | PPARG (0.36) | ALDH1A1PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL28806427 | 0.81 | MEN1 (0.38) | ALDH1A1PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL28775099 | 0.79 | PPARG (0.43) | PPARGPPARAAKR1C3AKR1C2PPARD | |
| SCHEMBL27713509 | 0.79 | AKR1B1 (0.36) | MAPTPPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL27713459 | 0.79 | PPARG (0.36) | GAAMAPTPPARGPPARAAKR1C3 | |
| SCHEMBL27713592 | 0.79 | ALDH1A1 (0.36) | ALDH1A1PPARGPPARAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |