Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 15/20 | 0.36 |
| ▸ | PPARA | Q07869 | 10/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909997 | 0.93 | PPARG (0.35) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27833814 | 0.91 | PPARG (0.37) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27813772 | 0.90 | PPARG (0.36) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27833813 | 0.84 | PPARG (0.36) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27950235 | 0.83 | RXRA (0.34) | MEN1KMT2APPARGPPARAPPARD | |
| SCHEMBL27713774 | 0.81 | ALDH1A1 (0.34) | ALDH1A1PPARGPPARAPPARDAKR1C3 | |
| SCHEMBL28775099 | 0.81 | PPARG (0.43) | MEN1POLBKMT2APPARGPPARA | |
| SCHEMBL28775106 | 0.81 | TRPV1 (0.34) | PPARGPPARAPPARDAKR1C3AKR1C2 | |
| SCHEMBL27713509 | 0.81 | AKR1B1 (0.36) | POLBSMN1; SMN2PPARGPPARAPPARD | |
| SCHEMBL27713592 | 0.81 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112441-B | Use of indole derivatives as NURR-1 activators for the treatment of parkinson's disease | FOURNIER LAB S A | 2013-07-10 | — | — | CN | disclosed |