Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775101 | 0.90 | PPARG (0.43) | PPARGPPARAPPARDMEN1NPC1 | |
| SCHEMBL27733702 | 0.88 | PPARG (0.46) | PPARGPPARAPPARDMEN1NPC1 | |
| SCHEMBL27713459 | 0.88 | PPARG (0.36) | PPARGPPARAPPARDMEN1RAB9A | |
| SCHEMBL27713509 | 0.85 | AKR1B1 (0.36) | PPARGPPARAPPARDNPC1POLB | |
| SCHEMBL27733811 | 0.84 | DYRK1A (0.49) | NPC1RAB9A | |
| SCHEMBL27713592 | 0.83 | ALDH1A1 (0.36) | PPARGPPARAPPARDNPSR1RORC | |
| SCHEMBL27833814 | 0.81 | PPARG (0.37) | PPARGPPARAPPARDMEN1POLB | |
| SCHEMBL28806427 | 0.81 | MEN1 (0.38) | PPARGPPARAPPARDMEN1POLB | |
| SCHEMBL27813772 | 0.81 | PPARG (0.36) | PPARGPPARAPPARDMEN1POLB | |
| SCHEMBL27713774 | 0.79 | ALDH1A1 (0.34) | PPARGPPARAPPARDAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |