Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.98 |
| ▸ | MEN1 | O00255 | 4/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.98 |
| ▸ | HBB | P68871 | 2/20 | 0.98 |
| ▸ | CASP1 | P29466 | 1/20 | 0.98 |
| ▸ | CASP7 | P55210 | 1/20 | 0.98 |
| ▸ | GLA | P06280 | 3/20 | 0.79 |
| ▸ | TP53 | P04637 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | STAT6 | P42226 | 1/20 | 0.79 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | GMNN | O75496 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxycamptothecin SCHEMBL25875 | 0.99 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL9384413 | 0.99 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL29350707 | 0.99 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL29929278 | 0.99 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL28094198 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL27638187 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL28836816 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL30872708 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL30426602 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydroxycamptothecin SCHEMBL27466705 | 0.98 | TOP1 (0.98) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243796-A | Insecticide composition and its processing method | UNIV ZHEJIANG FORESTRY (CN) | 2008-08-20 | — | — | CN | claimed |
| CN-100592871-C | Insecticide composition and its processing method | UNIV ZHEJIANG FORESTRY | 2010-03-03 | — | — | CN | disclosed |
| CN-101243796-A | Insecticide composition and its processing method | UNIV ZHEJIANG FORESTRY (CN) | 2008-08-20 | — | — | CN | disclosed |