Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.52 |
| ▸ | CA9 | Q16790 | 12/20 | 0.52 |
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA7 | P43166 | 6/20 | 0.52 |
| ▸ | CA5A | P35218 | 5/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.52 |
| ▸ | CA6 | P23280 | 4/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723049 | 1.00 | CA2 (0.52) | CA2CA9CA12CA1CA7 | |
| SCHEMBL28050659 | 0.83 | CA2 (0.62) | CA2CA9CA12CA1CA7 | |
| SCHEMBL31238706 | 0.78 | PTGS2 (0.50) | PTGS2 | |
| SCHEMBL28162626 | 0.78 | CA2 (0.52) | CA2CA9CA12CA1CA7 | |
| SCHEMBL7297451 | 0.78 | CA2 (0.50) | CA2CA9CA12CA1CA7 | |
| SCHEMBL27525349 | 0.78 | CA2 (0.52) | CA2CA9CA12CA1CA7 | |
| SCHEMBL7297449 | 0.78 | CA2 (0.50) | CA2CA9CA12CA1CA7 | |
| SCHEMBL13720250 | 0.78 | CA2 (0.52) | CA2CA9CA12CA1CA7 | |
| SCHEMBL11209918 | 0.75 | MAOB (0.42) | CA1LMNAALDH1A1 | |
| SCHEMBL11211999 | 0.75 | MAOB (0.42) | CA1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101245040-B | Process for producing 4-ethynyl benzene sulfonamide (I) | UNIV TONGJI | 2011-11-16 | — | — | CN | claimed |
| CN-101544585-A | Method for preparing (Z)-4-(2-bromovinyl) benzenesulfonimide | UNIV TONGJI | 2009-09-30 | — | — | CN | claimed |
| CN-101245040-A | Process for producing 4-ethynyl benzene sulfonamide (I) | UNIV TONGJI (CN) | 2008-08-20 | — | — | CN | claimed |
| CN-101245040-B | Process for producing 4-ethynyl benzene sulfonamide (I) | UNIV TONGJI | 2011-11-16 | — | — | CN | disclosed |
| CN-101544585-A | Method for preparing (Z)-4-(2-bromovinyl) benzenesulfonimide | UNIV TONGJI | 2009-09-30 | — | — | CN | disclosed |
| CN-101544585-A | Method for preparing (Z)-4-(2-bromovinyl) benzenesulfonimide | UNIV TONGJI | 2009-09-30 | — | — | CN | disclosed |
| CN-101544585-A | Method for preparing (Z)-4-(2-bromovinyl) benzenesulfonimide | UNIV TONGJI | 2009-09-30 | — | — | CN | disclosed |
| CN-101245040-A | Process for producing 4-ethynyl benzene sulfonamide (I) | UNIV TONGJI (CN) | 2008-08-20 | — | — | CN | disclosed |