Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775337 | 0.93 | LMNA (0.46) | MEN1KMT2ACNR1AVPR1ANPSR1 | |
| SCHEMBL27735364 | 0.90 | MEN1 (0.60) | MEN1KMT2ACNR1NPSR1CNR2 | |
| SCHEMBL27735250 | 0.87 | AVPR1A (0.55) | CNR1AVPR1ACNR2TPSAB1 | |
| SCHEMBL27735300 | 0.85 | CNR1 (0.40) | MEN1KMT2ACNR1AVPR1A | |
| SCHEMBL27714519 | 0.83 | AVPR1A (0.41) | CNR1AVPR1AKDM1ATPSAB1 | |
| SCHEMBL27735251 | 0.83 | MGLL (0.39) | CNR1AVPR1ASMN1; SMN2 | |
| SCHEMBL27735263 | 0.82 | CNR1 (0.39) | MEN1KMT2ACNR1AVPR1ASMN1; SMN2 | |
| SCHEMBL27714487 | 0.81 | MGLL (0.43) | MEN1KMT2ACNR1AVPR1ASMN1; SMN2 | |
| SCHEMBL27735273 | 0.80 | AVPR1A (0.38) | MEN1KMT2ACNR1AVPR1ATPSAB1 | |
| SCHEMBL27714472 | 0.79 | MGLL (0.43) | AVPR1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | claimed |
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |