Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714487 | 0.86 | MGLL (0.43) | CNR1AVPR1AMEN1KMT2AL3MBTL1 | |
| SCHEMBL27714472 | 0.84 | MGLL (0.43) | AVPR1AL3MBTL1ALDH1A1SMN1; SMN2CHRM1 | |
| SCHEMBL27714519 | 0.83 | AVPR1A (0.41) | CNR1AVPR1ACHRM1 | |
| SCHEMBL27714540 | 0.82 | MEN1 (0.48) | CNR1AVPR1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27735250 | 0.80 | AVPR1A (0.55) | CNR1AVPR1ACHRM1 | |
| SCHEMBL27735300 | 0.78 | CNR1 (0.40) | CNR1AVPR1AMEN1KMT2AL3MBTL1 | |
| SCHEMBL3099176 | 0.78 | AVPR1A (0.66) | AVPR1AALDH1A1CHRM1 | |
| SCHEMBL28771078 | 0.78 | AVPR1A (0.63) | AVPR1ACHRM1 | |
| SCHEMBL28775337 | 0.78 | LMNA (0.46) | CNR1AVPR1AMEN1KMT2AL3MBTL1 | |
| SCHEMBL27735308 | 0.75 | TPSAB1 (0.52) | CNR1TP53BP1L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | claimed |
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |