Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | INSR | P06213 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | LYN | P07948 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217108 | 0.89 | FNTA (0.41) | FNTAFNTBKDRAURKBPLK4 | |
| SCHEMBL5214990 | 0.86 | MAPT (0.41) | FNTAFNTBKDRAURKBMAPT | |
| SCHEMBL5216518 | 0.84 | CNR1 (0.48) | KDRAURKBMAPTLMNASMN1; SMN2 | |
| SCHEMBL27714643 | 0.82 | MAPT (0.43) | KDRROCK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28768848 | 0.82 | MAPT (0.39) | KDRMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27714640 | 0.82 | MAPT (0.43) | KDRMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL28769034 | 0.82 | MAPT (0.39) | KDRMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5218551 | 0.80 | MAPT (0.42) | KDRMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27714654 | 0.79 | AVPR1B (0.38) | KDRMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5215826 | 0.76 | MAPT (0.47) | MAPTLMNASMN1; SMN2TP53SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | claimed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |