Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224182 | 0.88 | MAPT (0.41) | AVPR1BMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL27714640 | 0.87 | MAPT (0.43) | MAPTLMNASMN1; SMN2TP53MEN1 | |
| SCHEMBL28768848 | 0.85 | MAPT (0.39) | MAPTLMNASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL27714643 | 0.85 | MAPT (0.43) | MAPTLMNASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL28769034 | 0.85 | MAPT (0.39) | AVPR1BMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL5220723 | 0.81 | SMN1; SMN2 (0.45) | AVPR1BMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL5219606 | 0.81 | MAPT (0.44) | MAPTLMNASMN1; SMN2TP53MEN1 | |
| Cyclopropane SCHEMBL27714655 | 0.80 | AOC3 (0.43) | AVPR1BMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL27714648 | 0.79 | FNTA (0.40) | MAPTLMNASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL5215826 | 0.79 | MAPT (0.47) | MAPTLMNASMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | claimed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |