Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.78 |
| ▸ | ABCC3 | O15438 | 3/20 | 0.78 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.78 |
| ▸ | HTR2A | P28223 | 2/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.78 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.78 |
| ▸ | RARA | P10276 | 1/20 | 0.78 |
| ▸ | RARB | P10826 | 1/20 | 0.78 |
| ▸ | RARG | P13631 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gliquidone SCHEMBL21824303 | 0.91 | CYP2C9 (0.79) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL29465034 | 0.88 | LMNA (1.00) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL15669239 | 0.88 | LMNA (1.00) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL37769 | 0.88 | LMNA (1.00) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL676846 | 0.88 | LMNA (0.98) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL15845544 | 0.82 | CYP2C9 (0.53) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| SCHEMBL8216020 | 0.82 | LMNA (0.87) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL28086518 | 0.81 | LMNA (0.82) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Glisolamide SCHEMBL38106 | 0.81 | LMNA (0.73) | CYP2C9LMNACYP3A4ABCC3ABCC4 | |
| Gliquidone SCHEMBL3112032 | 0.81 | CYP2C9 (0.72) | CYP2C9LMNACYP3A4ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277960-A | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK & CO INC (US) | 2008-10-01 | — | — | CN | disclosed |