Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393627 | 0.98 | BRD4 (0.51) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| Hydrogen Sulfide SCHEMBL27539552 | 0.95 | BRD4 (0.50) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| Methyl Alcohol SCHEMBL27626456 | 0.91 | BRD4 (0.51) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| Hydrogen Sulfide SCHEMBL27869470 | 0.90 | BRD4 (0.46) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| Boric Acid SCHEMBL29723852 | 0.90 | BRD4 (0.46) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| SCHEMBL10789751 | 0.89 | PTGS2 (0.60) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| SCHEMBL28228917 | 0.89 | PTGS2 (0.56) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| SCHEMBL29433489 | 0.89 | PTGS2 (0.60) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| SCHEMBL7265963 | 0.88 | BRD4 (0.45) | BRD4PTGS2ADRA2AADRA1DADRA1A | |
| SCHEMBL28044808 | 0.88 | BRD4 (0.49) | BRD4PTGS2ADRA2AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-B | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | INST PHARM & TOXICOLOGY AMMS | 2012-12-26 | — | — | CN | disclosed |
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |