Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.49 |
| ▸ | RPA1 | P27694 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714730 | 0.89 | MARS1 (0.74) | MARS1KMT2AMEN1ATMPPP1CA | |
| SCHEMBL9207624 | 0.84 | MARS1 (0.49) | MARS1KMT2AMEN1PPP1CARPA1 | |
| SCHEMBL8317362 | 0.82 | PTGS2 (0.49) | MARS1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL27694888 | 0.82 | KMT2A (0.71) | MARS1KMT2AMEN1ATMPPP1CA | |
| SCHEMBL27694772 | 0.81 | MEN1 (0.47) | MARS1KMT2AMEN1ATMPPP1CA | |
| SCHEMBL1831165 | 0.79 | MARS1 (0.74) | MARS1KMT2AMEN1PPP1CARPA1 | |
| SCHEMBL27714814 | 0.78 | MARS1 (0.48) | MARS1KMT2AMEN1ATMFABP3 | |
| SCHEMBL8742241 | 0.78 | RPA1 (0.78) | MARS1KMT2AMEN1PPP1CARPA1 | |
| SCHEMBL5473862 | 0.78 | RPA1 (0.78) | MARS1KMT2AMEN1ATMPPP1CA | |
| SCHEMBL9630621 | 0.78 | MARS1 (0.61) | MARS1KMT2AMEN1PPP1CARPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |