Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435711 | 0.82 | CA2 (0.50) | SLC1A1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL31519378 | 0.77 | SLC1A2 (0.55) | SLC1A1 | |
| SCHEMBL17311980 | 0.74 | TET2 (0.44) | OR51E2 | |
| SCHEMBL13873420 | 0.74 | TET2 (0.44) | OR51E2 | |
| SCHEMBL15398290 | 0.73 | CHRM1 (0.33) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL14164385 | 0.72 | NOS2 (0.47) | SLC1A1GRM3 | |
| SCHEMBL15485862 | 0.72 | NOS2 (0.47) | SLC1A1GRM3 | |
| SCHEMBL14087200 | 0.72 | NOS2 (0.47) | SLC1A1GRM3 | |
| SCHEMBL30552373 | 0.72 | NOS2 (0.47) | SLC1A1GRM3 | |
| SCHEMBL27809324 | 0.72 | GABRR1 (0.46) | FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109416359-A | For molecular imaging and/or the dimerization strategy and compound of radioimmunotherapy | 匹兹堡大学联邦系统高等教育 | 2019-03-01 | — | — | CN | disclosed |
| CN-101094847-B | Aryloxy-substituted benzimidazole derivatives | BANYU PHARMA CO LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-101094847-A | Aryloxy-substituted benzimidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |