Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315123 | 0.89 | AAK1 (0.41) | KMT2AAAK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7770451 | 0.89 | TDP1 (0.54) | TDP1MMP8MEN1KMT2ANPC1 | |
| SCHEMBL27535107 | 0.79 | SLC7A5 (0.40) | MEN1KMT2AAAK1SMN1; SMN2POLB | |
| SCHEMBL23012998 | 0.79 | SLC7A5 (0.40) | MEN1KMT2AAAK1SMN1; SMN2POLB | |
| SCHEMBL16795576 | 0.79 | MMP8 (0.60) | MMP8MEN1KMT2ANPC1TSHR | |
| SCHEMBL9556107 | 0.76 | MMP8 (0.62) | TDP1MMP8MEN1KMT2ANPC1 | |
| SCHEMBL7412568 | 0.75 | TDP1 (0.49) | TDP1MMP8MEN1KMT2ATSHR | |
| SCHEMBL8633650 | 0.75 | POLB (0.38) | TDP1MEN1KMT2ATSHRPOLB | |
| SCHEMBL12155250 | 0.75 | CTSK (0.40) | — | |
| SCHEMBL28386849 | 0.73 | AAK1 (0.39) | MEN1KMT2AAAK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101092373-B | Method for synthesizing optically active derivative of 5 - aryl - (S) - N - boc - alpha amino pentanoic acid | YAOMINGKANGDE NEW MEDICINES CO LTD SHANGHAI | 2012-06-27 | — | — | CN | disclosed |
| CN-101092373-A | Method for synthesizing optically active derivative of 5 - aryl - (S) - N - boc - alpha amino pentanoic acid | YAOMINGKANGDE NEW MEDICINES CO (CN) | 2007-12-26 | — | — | CN | disclosed |