Butadiene

Butadiene

SCHEMBL27714940

C=CC(C=C)=Cc1ccccc1.C=CC=C

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
AKR1C3 P42330 1/20 0.40
AKR1C1 Q04828 1/20 0.39
ESR1 P03372 1/20 0.39
AKT1 P31749 1/20 0.38
FBP1 P09467 3/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
PRMT1 Q99873 1/20 0.35
MAOB P27338 1/20 0.35
CYP2A6 P11509 1/20 0.35
TGM2 P21980 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL7850990 0.95 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL117901 0.95 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
Ethylene SCHEMBL27501133 0.93 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3AKR1C1ESR1
Iodide SCHEMBL6554697 0.93 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3AKR1C1ESR1
Styrene SCHEMBL9849012 0.88 ALDH1A1 (0.64) ALDH1A1TSHRAKR1C3AKR1C1ESR1
Styrene SCHEMBL27756737 0.86 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL372391 0.83 ALDH1A1 (0.39) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL1456820 0.83 ALDH1A1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1ESR1
Acrylonitrile SCHEMBL27815830 0.83 MCL1 (0.42) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL28555738 0.82 TP53 (0.53) ALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102206466-A Production method of styrene butadiene rubber adhesive QUANYI DUAN 2011-10-05 CN disclosed
CN-101268140-A Highly elastic polyvinyl chloride composition and products prepared using the same LG CHEMICAL LTD (KR) 2008-09-17 CN disclosed