SCHEMBL372391

SCHEMBL372391

C=CC=CC(C=C)=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
AKR1C3 P42330 1/20 0.35
MAOB P27338 1/20 0.34
AKR1C1 Q04828 1/20 0.34
ESR1 P03372 1/20 0.34
MAPT P10636 2/20 0.33
HDAC3 O15379 2/20 0.33
HDAC4 P56524 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC7 Q8WUI4 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC10 Q969S8 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC9 Q9UKV0 2/20 0.33
HDAC5 Q9UQL6 2/20 0.33
CYP2C9 P11712 2/20 0.33
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337661 0.92 ALDH1A1 (0.42) ALDH1A1TSHRAKR1C3MAOBAKR1C1
Pyridine SCHEMBL3284379 0.90 CYP11B2 (0.39) ALDH1A1TSHRMAPTLMNACYP1A2
SCHEMBL24093 0.85 ALDH1A1 (0.44) ALDH1A1TSHRMAOBMAPTHDAC3
SCHEMBL9422101 0.85 ALDH1A1 (0.44) ALDH1A1TSHRMAOBMAPTHDAC3
SCHEMBL954016 0.85 ALDH1A1 (0.44) ALDH1A1TSHRMAOBMAPTHDAC3
SCHEMBL11070168 0.83 ALDH1A1 (0.44) ALDH1A1TSHRAKR1C3MAOBAKR1C1
Butadiene SCHEMBL9420166 0.83 MAPT (0.42) ALDH1A1TSHRMAOBMAPTHDAC3
Water SCHEMBL6447465 0.83 MAPT (0.42) ALDH1A1TSHRMAOBMAPTHDAC3
Butadiene SCHEMBL27714940 0.83 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3MAOBAKR1C1
Benzene SCHEMBL7850990 0.83 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3MAOBAKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773528-B Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2024-01-19 CN claimed
CN-115850617-A High-vinyl SBS modifier and preparation method thereof 青岛科凯达橡塑有限公司 2023-03-28 CN claimed
CN-114773528-A Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2022-07-22 CN claimed
EP-1692230-B1 RAPID DISPERSING HYDROUS KAOLINS IMERYS KAOLIN INC (US) 2008-12-31 EP claimed
US-20070161736-A1 Rapid dispersing hydrous kaolins IMERYS KAOLIN, INC. 2007-07-12 US claimed
EP-1692230-A2 RAPID DISPERSING HYDROUS KAOLINS Imerys Kaolin, Inc. (US) 2006-08-23 EP claimed
WO-2005052066-A2 RAPID DISPERSING HYDROUS KAOLINS IMERYS KAOLIN, INC. (US) 2005-06-09 WO claimed
US-4789430-A DIMENSIONAL STABILITY; RESISTANCE TO DELAMINATION ARJOMARI-PRIOUX (FR) 1988-12-06 US claimed
JP-9227723-A None JP disclosed
CN-115028787-B Polar modifier system for high vinyl block copolymerization 戴纳索尔伊莱斯托米罗斯公司 2024-06-11 CN disclosed
CN-114773528-B Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2024-01-19 CN disclosed
CN-114773528-B Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2024-01-19 CN disclosed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
EP-3883978-B1 METHOD FOR PREPARING RANDOM LOW VINYL COPOLYMERS, COPOLYMERS PREPARED BY THIS METHOD, AND RUBBER MIXTURES BASED ON THESE COPOLYMERS SIBUR HOLDING PUBLIC JOINT STOCK CO (RU) 2023-07-19 EP disclosed
JP-H09227723-A TREAD RUBBER COMPOSITION FOR LOW FUEL COST TIRE TOYO TIRE & RUBBER CO LTD 1997-09-02 JP disclosed
US-5070150-A FREE RADICAL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-03 US disclosed
US-4669518-A Tire tread having high trans butadiene based elastomeric block copolymers and blends GENCORP INC. (US) 1987-06-02 US disclosed
US-4670502-A GOOD ROLLING, SKID AND ABRASION RESISTANCE GENCORP INC. (US) 1987-06-02 US disclosed
US-4616065-A COPOLYMER OF STYRENE OR ISOPRENE; TIRE TREADS GENCORP INC. (US) 1986-10-07 US disclosed
US-4370448-A Thermosetting composition combined high vinyl diolefin polymer with high vinyl low vinyl diolefin polymer PHILLIPS PETROLEUM COMPANY (US) 1983-01-25 US disclosed