Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961038 | 0.82 | GBA1 (0.46) | NOS3NOS1NOS2GBA1PRMT3 | |
| SCHEMBL9874798 | 0.80 | NPC1 (0.50) | GBA1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL7312019 | 0.77 | GBA1 (0.44) | NOS3NOS1NOS2GBA1PRMT3 | |
| SCHEMBL21241999 | 0.72 | — | — | |
| SCHEMBL2027845 | 0.71 | GBA1 (0.71) | GBA1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL674276 | 0.71 | GBA1 (0.71) | GBA1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL16949527 | 0.71 | — | — | |
| SCHEMBL5675291 | 0.69 | GBA1 (0.57) | GBA1PRMT3CARM1PRMT6PRMT1 | |
| Ammonia Solution, Strong SCHEMBL1432566 | 0.69 | GBA1 (0.68) | GBA1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL19226541 | 0.69 | GBA1 (0.47) | NOS3NOS1NOS2GBA1PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101044137-A | 2,4-di(aminophenyl)pyrimidine derivatives as plk inhibitors | BOEHRINGER INGELHEIM INT (DE) | 2007-09-26 | — | — | CN | disclosed |