SCHEMBL9874798

SCHEMBL9874798

CC1=CCC(Cc2ccccc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GBA1 P04062 1/20 0.47
CCR3 P51677 2/20 0.43
GRIN2B Q13224 1/20 0.41
HTR1A P08908 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CARM1 Q86X55 2/20 0.41
PRMT6 Q96LA8 2/20 0.41
PRMT3 O60678 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16692536 0.80 TSHR (0.53) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL4961038 0.80 GBA1 (0.46) GBA1CCR3GRIN2BHTR1ASIGMAR1
SCHEMBL7312019 0.79 GBA1 (0.44) ALDH1A1GBA1CCR3GRIN2BHTR1A
SCHEMBL31621838 0.78 CYP2A6 (0.42) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL25447679 0.78 TSHR (0.45) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL22112337 0.77 ALDH1A1 (0.42) ALDH1A1
SCHEMBL2563770 0.76 LMNA (0.45) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL11252858 0.74
SCHEMBL29338115 0.73 OPRM1 (0.46) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL2027845 0.73 GBA1 (0.71) ALDH1A1GBA1CCR3GRIN2BSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249976-B1 PROCESS FOR THE PRODUCTION OF CARBOXYLIC ACIDS BASF Aktiengesellschaft (DE) 1991-02-27 EP disclosed
EP-0249976-A1 Process for the production of carboxylic acids BASF Aktiengesellschaft (DE) 1987-12-23 EP disclosed