Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874798 | 0.79 | NPC1 (0.50) | GBA1CCR3GRIN2BHTR1ASIGMAR1 | |
| SCHEMBL4961038 | 0.77 | GBA1 (0.46) | GBA1CCR3GRIN2BHTR1ASIGMAR1 | |
| SCHEMBL27715499 | 0.77 | NOS3 (0.46) | GBA1CCR3GRIN2BHTR1ASIGMAR1 | |
| SCHEMBL30233465 | 0.73 | MEN1 (0.46) | ALDH1A1 | |
| SCHEMBL8701 | 0.71 | GBA1 (0.65) | GBA1CCR3GRIN2BCARM1PRMT6 | |
| SCHEMBL110859 | 0.71 | CALM1 (0.52) | GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL28384985 | 0.70 | GBA1 (0.50) | GBA1CCR3GRIN2BHTR1ASIGMAR1 | |
| SCHEMBL2027845 | 0.70 | GBA1 (0.71) | GBA1CCR3GRIN2BSIGMAR1CARM1 | |
| SCHEMBL674276 | 0.70 | GBA1 (0.71) | GBA1CCR3GRIN2BSIGMAR1CARM1 | |
| SCHEMBL3656584 | 0.69 | CALM1 (0.37) | GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560669-B1 | Piperazinyl-and piperidinyl-cyclohexenes and cyclohexanes | BRISTOL MYERS SQUIBB CO (US) | 1995-06-14 | — | — | EP | claimed |